华中农业大学信息学院生物信息研究生导师：王晓聪

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姓名:王晓聪

性别:男

职称:讲师

学位:博士

邮箱:wangxiaocong@mail.hzau.edu.cn

工作单位:

华中农业大学信息学院

研究方向:

计算生物化学，力场开发

教育经历:

2007.08 – 2015.12 佐治亚大学，化学系，博士

2003.09 – 2007.06 中国科学技术大学，化学系，学士

主要职历:

2018.04 – 至今 华中农业大学信息学院 讲师

2016.02 – 2018.02 佐治亚大学 复杂碳水化合物研究中心 博士后

科研成果:

1.Wang, X. C.; Woods, R. J., Insights into furanose solution conformations: beyond the two-state model. J. Biomol. NMR2016, 64 (4), 291-305.

2. Queiroz, I. N. L.;Wang, X. C.; Glushka, J. N.; Santos, G. R. C.; Valente, A. P.; Prestegard, J. H.; Woods, R. J.; Mourao, P. A. S.; Pomin, V. H., Impact of sulfation pattern on the conformation and dynamics of sulfated fucan oligosaccharides as revealed by NMR and MD. Glycobiology2015, 25 (5), 535-547.

3. Krishnamurthy, V. R.; Sardar, M. Y. R.; Ying, Y.; Song, X. Z.; Haller, C.; Dai, E. B.;Wang, X. C.; Hanjaya-Putra, D.; Sun, L. J.; Morikis, V.; Simon, S. I.; Woods, R. J.; Cummings, R. D.; Chaikof, E. L., Glycopeptide analogues of PSGL-1 inhibit P-selectin in vitro and in vivo. Nat. Commun.2015, 6, 12.

4. Hsu, C. H.; Park, S.; Mortenson, D. E.; Foley, B. L.;Wang, X. C.; Woods, R. J.; Case, D. A.; Powers, E. T.; Wong, C. H.; Dyson, H. J.; Kelly, J. W., The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate. J. Am. Chem. Soc.2016, 138 (24), 7636-7648.

5. Zhang, W. H.; Meredith, R.; Yoon, M. K.;Wang, X. C.; Woods, R. J.; Carmichael, I.; Serianni, A. S., Synthesis and O-Glycosidic Linkage Conformational Analysis of C-13-Labeled Oligosaccharide Fragments of an Antifreeze Glycolipid. J. Org. Chem.2019, 84(4), 1706-1724.

6. Zhang, W. H.; Turney, T.; Meredith, R.; Pan, Q. F.; Sernau, L.;Wang, X. C.; Hu, X. S.; Woods, R. J.; Carmichael, I.; Serianni, A. S., Conformational Populations of beta-(1 -> 4) O-Glycosidic Linkages Using Redundant NMR J-Couplings and Circular Statistics. J. Phys. Chem. B2017, 121 (14), 3042-3058.

7. Turney, T.; Pan, Q. F.; Sernau, L.; Carmichael, I.; Zhang, W. H.;Wang, X. C.; Woods, R. J.; Serianni, A. S., O-Acetyl Side-Chains in Monosaccharides: Redundant NMR Spin-Couplings and Statistical Models for Acetate Ester Conformational Analysis. J. Phys. Chem. B2017, 121 (1), 66-77.

8. Singh, A.; Tessier, M. B.; Pederson, K.;Wang, X. C.; Venot, A. P.; Boons, G. J.; Prestegard, J. H.; Woods, R. J., Extension and validation of the GLYCAM force field parameters for modeling glycosaminoglycans. Can. J. Chem.2016, 94 (11), 927-935.

参与发表著作：

1. Hadad, M. J.; Zhang, W. H.; Turney, T.; Sernau, L.;Wang, X. C.; Woods, R. J.; Incandela, A.; Surjancev, I.; Wang, A.; Yoon, M. K.; Coscia, A.; Euell, C.; Meredith, R.; Carmichael, I.; Serianni, A. S., NMR Spin-Couplings in Saccharides: Relationships Between Structure, Conformation and the Magnitudes of J(HH), J(CH) and J(CC) Values. In Nmr in Glycoscience and Glycotechnology, Kato, K.; Peters, T., Eds. Royal Soc Chemistry: Cambridge, 2017; Vol. 10, pp 20-100.