北京科技大学化生学院生物工程与传感技术研究中心研究生导师：杜鑫

导师信息来源：北京科技大学 2019-05-28　相关院校：北京科技大学

杜鑫

副教授/副研究员

办公地点：--化生楼302

办公电话：--

电子邮件：duxin@ustb.edu.cn

科研方向：具有阶层（多级）结构的纳米材料的可控制备及其在纳米药物基因递送载体、纳米催化剂、多功能自清洁纳米涂层、纳米马达等领域的应用研究

简历

2014/9~至今：北京科技大学，化学与生物工程学院，生物传感中心，副教授/副研究员，硕导； 2012/07~2014/08：澳大利亚阿德莱德大学，化学工程学院，加入乔世璋教授课题组，博士后研究员；2007/09~2012/06：中国科学院理化技术研究所，物理化学专业，博士学位，导师：贺军辉研究；2003/09~2007/06：南开大学，化学学院材料化学专业，理学学士学位。

科研业绩

北京科技大学高水平拔尖人才引进计划，启动经费30万；国家自然科学基金-青年基金，29.82万; 中央高校基础科研业务费研究项目，10万；中央高校基础科研业务费研究项目，10万；横向经费，25.6万，中国科学院光化学转换与功能材料重点实验室开放课题，2万元；北京科技大学基本科研业务费-化生学院特色理科建设项目，2万元。

获得奖励/专利

1. 新南威尔士大学副校长博后奖学金；2.中科院三好学生标兵、所长奖学金、三星奖学金；3. 五项已经授权的发明专利，三项在申请中。

招生计划

每年招收2名硕士生，欢迎本科生来实习。

代表性论文论著

目前，在Adv. Mater., Adv. Funct. Mater., Biomaterials, Small等化学、材料和生物类重要期刊发表SCI研究论文80多篇，其中第一和通讯作者文章45篇，影响因子大于10的有5篇，引用超过2600次，高被引论文4篇，H指数为28，研究成果被国际网络新闻ACS News Service Weekly PressPac, ChemistryView, MaterialViews等进行了广泛关注报道。

代表性论文论著

1.X. Du*, F. Kleitz*, X. Li, H. Huang, X. Zhang, S. Z. Qiao*,Disulfide-bridged organosilica frameworks: Designed synthesis, redox-triggered biodegradation, and nanobiomedical applications" Adv. Funct. Mater.2018, 28, 1707325.

2.X. Du*, C. Zhao, M. Zhou, T. Y. Ma, H. Huang, M. Jaroniec, X. Zhang, S. Z. Qiao*, Hollow carbon nanospheres with tunable hierarchical pores for drug, gene and photothermal synergistic treatment. Small 2017, 13, 1602592.

3. X. Du*, C. Zhao, Y. Luan*, C. Zhang, M. Jaroniec, H. Huang, X. Zhang, S. Z. Qiao*, Dendritic porous yolk@ordered mesoporous shell structured heterogeneous nanocatalysts with enhanced stability. J. Mater. Chem. A2017, 5, 21560.

4. B. Shi,* X. Du*, J.Chen, L. Fu, M. Morsch, A. Lee, Y. Liu, N. Cole, R. Chung, Multifunctional hybrid nanoparticles for traceable drug delivery and intracellular microenvironment controlled multistage drug release in neurons. Small 2017, 13, 1603966

5. M. Zhou, X. Du*, W. Li, X. Li, H. Huang, Q. Liao, B. Shi, X. Zhang, M. Zhang*, One-pot synthesis of redox-triggered biodegradable hybrid nanocapsules with a disulfide-bridged silsesquioxane framework for promising drug delivery. J. Mater. Chem. B 2017, 5, 4455

6. X. Du, X. Li, L. Xiong, X. Zhang*, F. Kleitz, S. Z. Qiao*,Mesoporous silica nanoparticles with organo-bridged silsesquioxane framework as innovative platforms for bioimaging and therapeutic agent delivery.

Biomaterials 2016, 91, 90.

7. X. Du*, X. Li, H. Huang, J. He, X. Zhang, Dendrimer-like hybrid particles with tunable hierarchical pores. Nanoscale 2015, 6173.

8. X. Du, S. Z. Qiao*, Dendritic silica particles with center-radial pore channels: promising platforms for catalysis and biomedicine applications. Small 2015, 11, 392.

9. X. Du, B. Y. Shi, J. Liang, J. Bi. S. Dai, S. Z. Qiao*, Developing functionalized dendrimer-like silica nanoparticles with hierarchical pores as advanced delivery nanocarriers. Adv. Mater. 2013, 25, 5981.

10. X. Du, L. Xiong, Y. Tang, S. Dai, F. Kleitz, S. Z. Qiao*, Intracellular microenvironment-responsive dendrimer-like mesoporous nanohybrids for responsive, traceable, effective and safe intracellular gene delivery. Adv. Funct. Mater. 2014, 24, 7627.

11. X. Du, B. Shi, Y. Tang, S. Dai, S. Z. Qiao*, Label-free dendrimer-like silica nanohybrids for traceable and controlled gene delivery. Biomaterials 2014, 35, 5580.

12. X. Du, B. Y. Shi, L. Xiong, S. Dai, S. Z. Qiao*, ɣ-PGA coated mesoporous ailica nanoparticles with covalently attached prodrug for enhanced cellular uptake and intracellular GSH-responsive release. Adv. Healthcare. Mater. 2015, 4, 771.

13. X. Du, L. Yao, J. He*,One-pot fabrication of noble-metal nanoparticles that are encapsulated in hollow silica nanospheres: dual roles of poly (acrylic acid), Chem. Eur. J. 2012, 18, 7878.

14. X. Du, J. He*, Amino-functionalized silica nanoparticles with center-radially hierarchical mesopores as ideal catalyst carriers. Nanoscale2012, 4, 852.

15. X. Du, J. He*, Facile fabrication of hollow mesoporous silica nanospheres for superhydrophilic and visible/ Near-IR antireflection coatings. Chem. Eur. J. 2011, 17, 8165.

16. X. Du, J. He, A self-templated etching route to surface-rough silica nanoparticles for superhydrophobic coatings. ACS Appl. Mater. Interface 2011, 3, 1269.

研究生培养情况

赵彩霞（优秀毕业生和毕业论文），李玮克（优秀毕业生,1等奖学金），周梦芸（1等奖学金），王雨露（国家奖学金），轩晓腻，邢义（已毕业学生均有高水平论文发表）