湖南师范大学生命科学学院生物化学与分子生物学研究生导师：陈平

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湖南师范大学生命科学学院生物化学与分子生物学研究生导师陈平介绍如下：

陈平,二级教授，生物化学博士。 1962年11月生， 1983年毕业于湖南大学化学化工学院分析化学专业,1988年获湖南师范大学生命科学学院生物化学与分子生物学硕士学位， 2005 年获生物化学与分子生物学博士学位。 2001 年曾作为访问学者在美国佛罗里达大学分子细胞生物化学系作访问研究。近年来主要从事蛋白质化学与蛋白质组学的研究。主持了国家 973 项目子课题“膜蛋白以及膜蛋白复合体的分离鉴定新方法新技术”、国家 973 前期项目“与血管生成启动相关的质膜蛋白质组研究”、国家自然科学基金项目“肝脏再生过程中血窦内皮细胞功能蛋白质分析”、“肝再生过程中质膜微区蛋白质及复合物动态变化研究”、“肝再生过程中肝血窦内皮细胞动态调控的信号途径及机制研究”、“多肽探针研究Nav1.7调节前列腺癌PC3细胞转移的分子机制 ” ，以及湖南省科技厅重点项目“细胞膜蛋白质组研究方法发展及其在神经系统细胞质膜蛋白质组研究中的应用”的研究；并作为主要骨干研究人员参与并完成了国家科技攻关计划“人类健康肝脏蛋白质组表达谱以及国家 973 项目“重要疾病的蛋白质组学研究”等研究工作；曾获 2007 年及 2003 年湖南省科技厅科技进步奖一等奖和 1999 年国家教育部科技进步奖三等奖以及 1 项国家专利（专利号 为： ZL 2004 1 0023089 X ）。在“ Journal of Neurochemistry ”、“ Journal of Proteome Research ” 等杂志上已发表相关论文8 0 余篇，参编著作三部。

近五年主持的各类国家科技计划项目情况:

近年来以通讯作者或第一作者发表的主要研究论文

1.Jiang M, Qi L, Liu P, Wang Z, Duan Z, Wang Y, Liu Z, Chen P*,. Selective enrichment and desalting of hydrophilic peptides using graphene oxide. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Aug 1; 1027:149-157.

2.Ge L, Jiang M, Duan D, Wang Z, Qi L, Teng X, Zhao Z, Wang L, Zhuo Y, Chen P*, He X, Lu M.  Secretome of Olfactory Mucosa Mesenchymal Stem Cell, a Multiple Potential Stem Cell.  Stem Cells Int. 2016:1243659.

3.Yu J, Lin S, Wang M, Liang L, Zou Z, Zhou X, Wang M, Chen P*, Wang Y. Metastasis suppressor 1 regulates neurite outgrowth in primary neuron cultures.Neuroscience. 2016, 333:123-131 

4.Cheng Zhang, Jinyan Li, Xinhong Guo, Baode Zhu, Wenjun Xiao, Ping Wang, Miao Jiang, Shuai Hu, Xiutao Lu, Zhuang He, Ping Chen*. LecRK-VII.1, a Lectin Receptor-Like Kinase, Mediates the Regulation of Salt Stress and Jasmonic Acid Response in Arabidopsis. Journal of Plant Growth Regulation. 2016,12

5.Li J, Gao J, Jiang M, Chen J, Liu Z, Chen P*, Liang S. Rat liver sinusoidal surface N-linked glycoproteomic analysis by affinity enrichment and mass spectrometric identification. Biochemistry (Mosc). 2015 Mar;80(3):260-75

6.Zhang W, Long J, Zhang C, Cai N, Liu Z, Wang Y, Wang X, Chen P*, Liang S.  A method combining SPITC and 18O labeling for simultaneous protein identification and relative quantification. J.Mass.Spectrom. 2014,49(5):400-408 

7.Wang L, Jiang M, Duan D, Zhao Z, Ge L, Teng X, Liu B, Liu B, Chen P*, Lu M.Hyperthermia-conditioned OECs serum-free-conditioned medium induce NSC differentiation into neuron more efficiently by the upregulation of HIF-1 alpha and binding activity.Transplantation. 2014,97(12):1225-1232 

8.Rui Cao, Ke Chen, Qin Song, Yi Zang, Jia Li, Xianchun Wang, Ping Chen*and Songping Liang. Quantitative Proteomic Analysis of Membrane Proteins Involved in Astroglial Differentiation of Neural Stem Cells by SILAC Labeling Coupled with LC–MS/MS. J.Proteome Res., 2012, 11 (2)：829–838     

9.Shi N, Tian C, Liang X, Jiang P, Liang L, Zhou L, Shu Y. Chen P*，Wang Y. Proteome analysis of actin filament a ssociated proteins in the postnatal rat cerebellum. Neuroscience.2012，227: 90-101.

10.Chunliang Xie, Nvying Liu, Jia Long, Cheng Tang, Jianglin Li, Linju Huo, Xianchun Wang, Ping Chen*, Songping Liang.  Blue Native/SDS-PAGE Combined with iTRAQ Analysis Reveals Advanced Glycation Endproducts-Induced Changes of Synaptosome Proteins in C57 BL/6 Mice.  Electrophoresis.2011, 32: 2194–2205   

11.Liu Y, Teng X, Yang X, Song Q, Lu R, Xiong J, Liu B, Zeng N, Zeng Y, Long J, Cao R, Lin Y, He Q, Chen P*, Lu M, Liang S.  Shotgun proteomics and network analysis between plasma membrane and extracellular matrix proteins from rat olfactory ensheathing cells. Cell transplantation.  2010,19(2):133-146.     

12.Cao R, Liu Y, Chen P*, Lv R, Song Q, Sheng T, He Q, Wang Y, Wang X, Liang S. Improvement of hydrophobic integral membrane protein identification by mild performic acid oxidation-assisted digestion.  Anal Biochem. 2010 ,15;407(2):196-204. 

13.Xuanwen Li, Li Xiong, Chunliang Xie, Jia Cao, Huobao Deng, Yong Lin, Rui Cao, Jianglin Li, Ping Chen* , Songping Liang.  Proteomics analysis of plasma membrane from liver sinusoidal endothelial cells after partial hepatectomy by an improved two-dimensional electrophoresis. Molecular and Cellular Biochemistry2010，344（1-2）： 137-150.   

14.Li Xuanwen, Xie Chunliang, Jin Qihui, Liu Minhjun, He Quanyuan, Cao Rri, Lin Ying, Li Jianglin, Li Yan, Chen Ping*, Liang Songping. Proteomic Screen for Multiprotein Complexes in Synaptic Plasma Membrane from Rat Hippocampus by Blue Native Gel Electrophoresis and Tandem Mass Spectrometry， Journal of Proteome Research，2009，8：3475-3486   

15.Chen Ping, Zhang Lijun, Li Xuanwen, Wang Xie, Cao Rui, Liu Zhen,Cao Rui, Xiong Jixian, Peng Xia, Wei Yingjuan, Wang Xianchun, and Liang Songping.Evaluation of strategy for analyzing mouse liver plasma membrane proteome.Science in China Series C:Life Sciences. 2007,50(6)：731-738                       

16.Chen Ping, Li Xuanwen, Sun Yalan, Liu Zhen,Cao Rui, He Quanyuan, Wang Meichi, Xiong Jixian, Xie Jinyun, Wang Xianchun, and Liang Songping. Proteomic analysis of rat hippocampus plasma membrane:characterization of potential neuronal-specific plasma membraneproteins. Journal OfNeurochemistry. 2006,98：1126-1140 

17.Chen Ping, Nie Song，Wang Xiangchun, Liang Songping. De nove sequencing of tryptic peptides sulfonated by 4-sulfophenyl isothiocyanate for unambiguous protein identification using post-source decay matrix-assisted laser desorption/ionization mass spectrometry.  Rapid Commun. Mass Spectrom，2004,18:191-198.     

18.陈平参编著作《CLINICALRESEARCHAND TREATMENT APPROACHES TO AFFECTIVE DISORDERS》（英文）, 欧洲INTECH出版社，2012年