中国药科大学中药学院研究生导师介绍：陆续

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陆续，博士，硕士研究生导师。2013年6月毕业于上海交通大学植物学专业，获理学博士学位，论文获选为2015年度上海市优秀博士学位论文。主要从事生药活性成分与生物技术方面的研究。作为课题负责人，先后主持国家自然科学基金、江苏省自然科学基金、南京大学生物医药国家重点实验室开放研究基金等。迄今已在New Phytologist, Molecular Plant, PLoS ONE, Industrial Crops and Products等杂志发表研究论文20余篇，获授权国家发明专利4项。

研究方向：

1.药用植物次生代谢调控和萜类生物合成

2.药用植物分子生物学

3.药用植物代谢组学

目前承担课题情况：

1.国家自然科学基金项目名称：银杏内酯生物合成途径相关P450基因的克隆与功能研究；项目批准号：81403043；项目起止年月：2015.1-2017.12；

2.江苏省自然科学基金项目名称：AP2/ERF类转录因子在三七三萜皂苷生物合成途径中的调控机制研究；项目批准号：BK20140663；项目起止年月：2014.7-2016.6；

3.中国药科大学科研启动基金项目名称：银杏内酯合成途径关键基因的表达研究；项目批准号：ZJ14115；项目起止年月：2014.1-2015.12。

研究成果

1.代表性论文（*为通讯作者）

1)Xu Lu, Ling Zhang, Fangyuan Zhang,Weimin Jiang, Qian Shen, Lida Zhang, Zongyou Lv, GuofengWang, Kexuan Tang*. 2013. AaORA, a trichome-specific AP2/ERF transcription factor of artemisia annua, is a positive regulator in the biosynthesis of artemisinin and disease resistance to Botrytis cinerea. New Phytologist.198(4): 1191-202.

2)Xu Lu, Weimin Jiang, Ling Zhang, Fei Zhang, Fangyuan Zhang, Qian Shen, Guofeng Wang, Kexuan Tang*. 2013. AaERF1 positively regulates the resistance to B. cinerea in Artemisia annua. PLoS One. 8(2): e57657.

3)Xu Lu, Qian Shen, Ling Zhang, Fangyuan Zhang, Weimin Jiang, Zongyou Lv, Tingxiang Yan, Xueqing Fu, Guofeng Wang, Kexuan Tang*. 2013. Promotion of artemisinin biosynthesis in transgenic Artemisia annua by overexpressing ADS, CYP71AV1 and CPR genes. Industrial Crops and Products. 49: 380-385.

4)Xu Lu,  Fangyuan Zhang, Qian Shen ,Weimin Jiang, Qifang Pan, Zongyou Lv, Tingxiang Yan, Xueqing Fu, Yuliang Wang, Hongmei Qian, Kexuan Tang*. 2014. Overexpression of Allene Oxide Cyclase Improves the Biosynthesis of Artemisinin in Artemisia annua L. PLoS One. 9(3): e91741.

5)Xu Lu, Xiuyan Lin, Qian Shen, Fangyuan Zhang, Yueyue Wang, Yunfei Chen, Tao Wang, Shaoyan Wu, Kexuan Tang*. 2011. Characterization of the Jasmonate Biosynthetic Gene Allene Oxide Cyclase in Artemisia annua L., Source of the Antimalarial Drug Artemisinin. Plant Molecular Biology Reporter. 29: 489-497.

6)Xu Lu, Weimin Jiang, Ling Zhang, Fangyuan Zhang, Qian Shen, Tao Wang, Yunfei Chen, Shaoyan Wu, Zongyou Lv, Erdi Gao, Bo Qiu, Kexuan Tang*. 2012. Characterization of a novel ERF transcription factorin Artemisia annua and its induction kinetics after hormones and stress treatments. Molecular Biology Reports. 39(10): 9521-9527.

7)Xu Lu, Fangyuan Zhang, Weimin Jiang, Xiuyan Lin, Yunfei Chen, Qian Shen, Tao Wang, Shaoyan Wu, Xiaofen Sun, Kexuan Tang*. 2012. Characterization of the first specific jasmonate biosynthetic pathway gene allene oxide synthase from Artemisia annua. Molecular Biology Reports. 39(3): 2267-2274.

8)Xu Lu, Wei Zhou , Feng Gao*. 2010. Localization of 45S rDNA and DFR gene of Citrus sinensis Osbeck cv. Ruby. Biologia Plantarum. 54 (4): 798-800.

9)Xu Lu, Wei Zhou, Feng Gao*. 2009. Cloning, characterization and localization of CHS gene from blood orange, Citrus sinensis (L.) Osbeck cv. Ruby. Molecular Biology Reports. 36(7): 1983-90.

10)Weimin Jiang1, Xu Lu1, Bo Qiu, Fangyuan Zhang, Qian Shen, Zongyou Lv, Xueqing Fu, Tingxiang Yan, Erdi Gao, Mengmeng Zhu, Lingxian Chen, Ling Zhang, Guofeng Wang, Xiaofen Sun, Kexuan Tang*. 2014. Molecular Cloning and Characterization of a Trichome-Specific Promoter of Artemisinic Aldehyde Δ11(13) Reductase (DBR2) in Artemisia annua. Plant Molecular Biology Reporter. 32: 82-91.

2.专利

1)青蒿AaORA蛋白及编码基因、转基因青蒿植株的获得方法.唐克轩，陆续，江伟民，张凌，张利达，张芳源，沈乾，吕宗友,高尔娣.ZL201210014227.2.已授权。

2）AaORA基因启动子及其用途.唐克轩，陆续，张芳源，沈乾，张凌，江伟民，吕宗友.ZL201210384850.7.已授权。

3）采用水培技术快速繁殖转基因青蒿的方法,唐克轩,陆续,张凌,吴韶龑,江伟民,张芳源,沈乾.ZL201110340421.5.已授权。

4)转DBR2基因提高青蒿中青蒿素含量的方法.唐克轩,沈乾,陈韵斐,王涛,吴韶龑,陆续.ZL201210014227.2.已授权。

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