中国药科大学

情况简介：

戴振亚，2000年在南京大学获得学士学位，专业为化学，2005年10月在南京大学获得博士学位，专业为有机化学，2005年11月至2007年8月在德国莱布尼兹催化研究所从事博士后研究，2007年8月至今在中国药科大学担任教师，并于2008年12月被聘为副教授。目前主持国家自然科学基金青年教师基金一项，参与江苏省自然科学基金一项。目前发表论文23篇，其中SCI收录16篇。联系方式：daizhenya@hotmail.com，15951867995。

研究方向：不对称催化，不对称合成，手性药物合成，药物合成新方法研究。

发表论文目录：

1.Jiangtao Sun, Chengjian Zhu*, Zhenya Dai, Minghua Yang, Yi Pan, Hongwen Hu. Efficient Asymmetric Oxidation of Sulfides and Kinetic Resolution of Sulfoxides Catalyzed by Vanadium Salan System. J. Org. Chem. 2004, 69, 8500-8503.
2.Zhenya Dai, Chengjian Zhu*, Minghua Yang, Yi Pan*. Asymmetric addition of organogallium to aldehydes catalyzed by chiral titanium catalyst. Tetrahedron: Asymmetry. 2005, 16，605－608.
3. Zhenya Dai, Chengjian Zhu*, Yi Pan*. Utilization of organogallium and organoindium compounds as alkylation reagents in organic synthesis: the addition of trialkylgallium and trialkylindium to aldehydes catalyzed by Lewis acids. Applied Organometallic Chemistry 2005, 7, 898-902.
4.Haibing Zhu, Zhenya Dai, Wei Huang, Kai Cui, Shaohua Gou*, Chenjian Zhu*. Chiral copper(II) complexes of optically active Schiff bases: syntheses, crystal structure and asymmetric oxidation of methyl phenyl sulfide with hydrogen peroxidePolyhedron 2004, 23, 1131-1137
5.Zhenya Dai, Detlef Heller, Anke Spannenberg, Hans-Joachim Drexler. Crystal structure of (η4-cycloocta-1,5-dien)-((+)-1,1'-bis((2R,4R)-2,4-diethyl-phosphotano)-ferrocene)-rhodium(I) tetrafluoroborate, [Rh(C8H12)Fe(C12H18FeP)2][BF4]  Z. Krist. (NCS) 2007, 222, 109.
6.Zhenya Dai, Detlef Heller, Angelika Preetz, Hans-Joachim Drexler. Crystal structure of (η4-cycloocta-1,5-dien)-N-(2-(diphenylphosphinooxy)-3-(naphthalen-1-yloxy)propyl)-N-(pentan-3-yl)-1,1-diphenylphosphinamine-rhodium(I)tetrafluoroborate, [Rh(C8H12)(C42H43NO2P2)][BF4] Z. Krist. (NCS) 2007, 222, 111.
7.Ralph Jackstell, Zhenya Dai, Thomas Schmidt, Detlef Heller, Hans-Joachim Drexler. Crystal structure of 1-(2-(dicyclohexylphosphinophenyl)pyrol-2-dicyclohexylphosphino-rhodium(I) norborna-2,5-diene tetrafluoroborate tetrahydrofuran hemisolvate, [Rh(C34H51NP2)(C7H8)][BF4] 0.5C4H8O, and 1-(2-(dicyclohexylphosphinophenyl)pyrol-2-dicyclohexylphosphino-rhodium(I) (Z,Z)-cycloocta-1,5-diene tetrafluoroborate, [Rh(C34H51NP2)(C8H12)][BF4] Z. Krist. (NCS) 2007, 222, 458.
8.Angelika Preetz, Hans-Joachim Drexler, Christian Fischer, Zhenya Dai, Armin Borner, Wolfgang Baumann, Anke Spannenberg, Richard Thede, Detlef Heller. Rhodium catalyst catalyzed asymmetric hydrogenation-Transfer of the precatalyst into active species. Chemistry: A European Journal 2008, 14, 1445.
9.Thomas Schmidt, Zhenya Dai, Hans-Joachim Drexler, Wolfgang Baumann, Christian Jäger, Dietmar Pfeifer, Detlef Heller*. Novel contributions to the mechanism of the enantioselective hydrogenation of dimethyl itaconate with rhodium complexes. Chemistry: A European Journal 2008, 14, 4469-4471.
10.Thomas Schmidt, Zhenya Dai, Hans-Joachim Drexler, Detlef Heller* The major/minor concept:dependence of the selectivity of homogeneously catalyzed reactions on the reactivity ratio and concerntration of the intermediates. Chemistry: An Asian Journal 2008, 1170-1180.
11.Jiangtao Sun, Zhenya Dai, Minghua Yang, Xu Pan, Chengjian Zhu* Vanadium-salan catalyzed enantioselective ring-opening of meso-epoxides with aromatic amines. Synthesis, 2008, 13, 2100-2104.
12.Jiangtao Sun*, Minghua Yang, Zhenya Dai, Chengjian Zhu*, Hongwen Hu Synthesis of Optically Active 2,5-Dialkylcyclohexane-1,4-diols and Their Application in the Asymmetric Oxidation of Sulfides. Synthesis, 2008, 13, 2513-2518.
13.Jiangtao Sun, Xu Pan, Zhenya Dai, Chengjian Zhu* Synthesis of new Schiff base-camphorsulfonyl amide ligands and in situ screening in asymmetric addition of organozinc reagents to aldehydes. Tetrahedron: Asymmetry 2008, 19, 2451-2457.
14.Jiangtao Sun, Zhenya Dai*, Changsi Li, Xu Pan, Chengjian Zhu* Enantionselective pinacol coupling reaction of aromatic aldehydes catalyzed by chiral vanadium catalyst. Jouranl of Organometallic Chemistry 2009, 3219-3221.
15.Thomas Schmidt, Hans-Joachim Drexler, Jiangtao Sun, Zhenya Dai, Wolfgang Baumann, Angelika Preetz, Detlef Heller* Unusual Deactivation in the Asymmetric Hydrogenation of Itaconic Acid. Advanced Synthesis & Catalysis 2009, 351(5), 750-754.
16.Xiaoyang Dong, Ziyu Wang, Daorui Huang, Pei Xu, Zhenya Dai*, Synthesis of New Chiral Phase Transfer Catalysts and their Application in the Asymmetric Alkylation of Glycine Derivatives. Austin Journal of Analytical and Pharmaceutical Chemistry. 2014, 1(1), 3-5.
17.Ziyu Wang, Daorui Huang, Pei Xu, Xiaoyang Dong, Xiaolong Wang and Zhenya Dai *The asymmetric alkylation reaction of glycine derivatives catalyzed by the novel chiral phase transfer catalysts Tetrahedron Lett. 2015, 56, 1067-1071.
18.Xiaoyang Dong, Pei Xu, Ziyu Wang, Daorui Huang, Zhenya Dai*. Asymmetric sulfenylation of glycine derivative catalyzed by the novel chiral phase transfer catalysts. Austin J Anal Pharm Chem. 2015, 2(1), 1032.
19.Ziyu Wang, Xueyan Zhang, Pei Xu, Daorui Huang, Xiaolong Wang, Zhenya Dai*. Research on phase transfer catalytic reactions and their application in drug synthesis. Austin J Anal Pharm Chem. 2015, 2(1), 1033.
20.Lin Qiu, Daorui Huang, Guangyang Xu, Zhenya Dai, Jiangtao Sun*. Realized C−H Functionalization of Aryldiazo Compouds via Rhodium Relay Catalysis. Org. Lett. 2015, 17, 1810-1813.
21.李长思，戴振亚*等地尔硫卓中间体的合成工艺改进药学与临床研究2011,19,184-185.
22.王永超，戴振亚*等地尔硫卓中间体a,b-三元腈的合成药学与临床研究2011,19,470-471
23.刘洋，戴振亚*等氯沙坦合成工艺改造药学与临床研究2011,19,89-90
24.李长思，戴振亚*等脯氨酸催化的酮的不对称a-硫代反应药学与临床研究2010,18,243-246.
25.袁飞鹏，戴振亚*等脯氨酸催化的醛的不对称a-硫代反应药学进展2010,34,554-558.
26.卢协勤，戴振亚*等相转移催化的甘氨酸叔丁酯衍生物的硫代反应河北医药2012,34,1075-1077.
27.董晓阳，戴振亚*等不对称小分子催化合成的最新进展及其在药物合成中的应用中国药科大学学报2013,44,193-201.

申报及授权专利目录：

1.戴振亚，袁飞鹏等，罗本考昔的一种制备方法，专利授权号：CN102311355B.
2.戴振亚，袁飞鹏等，马氟考昔的一种制备方法，专利号：201210063799.
3.戴振亚，王永超等，一种手性相转移催化剂及其合成方法，专利号：201210085648.
4.戴振亚，王永超等，一种甘氨酸叔丁酯衍生物的不对称烷基化方法，专利号：201210085610.
5.戴振亚，袁飞鹏等，R-4-苄氧吡咯烷的一种制备方法，专利号：201210085627.
6.王森，曹鑫，曹聪，戴振亚，陆爱军，HDM2和HDMX双重抑制剂3－腈基喹啉衍生物及其制备方法与应用专利授权号：CN103804292A.
7.戴振亚，董晓阳等，一种新型手性相转移催化剂的合成及其应用，专利号：201410088280.6.
8.戴振亚，王子昱，黄道锐，徐沛一种环状金鸡纳碱季铵盐化合物的制法以及用途,专利号：201410455252.3.
9.王森，曹鑫，戴振亚，曹聪，张凌霄，(+)-生物素的制备方法，CN103833769A.
10.戴振亚，赵云德，王子昱，张学艳，许莎莎，依托考昔的一种合成方法，CN104693113A.