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西南大学生命技术学院教授简介--何华伟
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ruier123
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发表于 2015-06-17 09:06
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何华伟

http://sklsgb.swu.edu.cn/cn/uploads/allimg/130106/2-13010610295O61.JPG


博士,教授,
入选重庆市第三批“百名海外高层次人才集聚计划”

简历:

2011.5-             西南大学生物技术学院,家蚕基因组生物学国家重点实验室  重庆,中国
教授,入选重庆市第三批“百名海外高层次人才集聚计划”
2008.1-2011.4       德克萨斯州州立大学西南医学中心(达拉斯)药理系和生物化学系,美国
博士后,研究方向:信号传导,生物物理学,生物化学与分子生物学
2002.9-2008.7   清华大学生物科学与技术系,北京,中国  
博士,专业:生物化学与分子生物学  
1998.9-2002.7   北京林业大学生命科学学院,北京,中国
学士,专业:生物学

主要科研领域与方向:

研究方向:家蚕发育生物学,家蚕发育过程中的信号传导及调控

代表性论文:


  • Yuxiao Wang*, Huawei He*, Nishi Srivastava, Sheikh Vikarunnessa, Yong-bin Chen, Jing Jiang, Christopher W. Cowan & Xuewu Zhang. Plexins are GTPase Activating Proteins for Rap and are Activated by Induced Dimerization. Science Signaling. 2011 5(207): ra6 (Available online on 17 January 2012) (*, co-first author).
  • Yejing Wang, Huawei He, Sen Li. Effect of Ficoll 70 on Thermal Stability and Structure of Creatine Kinase. Biochemistry (Moscow). 2010 75(5):648-54.
  • Huawei He, Taehong Yang, Jonathan R. Terman & Xuewu Zhang. Crystal structure of the plexin A3 intracellular region reveals an autoinhibited conformation through active site sequestration. Proc. Natl. Acad. Sci. U.S.A. 2009 106(37):15610-5.
  • Zhu Jiang, He Hua-Wei, Li Sen. Macromolecular crowding enhances thermal stability of rabbit muscle creatine kinase. Tsinghua Science and Technology. 2008 13(4):454-9.
  • He Hua-Wei*, Feng Shan*, Pang Min, Zhou Hai-Meng, Yan Yong-Bin. Role of the linker between the N- and C-terminal domains in the stability and folding of rabbit muscle creatine kinase. Int. J. Biochem. Cell Biol. 2007 39(10):1816-27 (*, co-first author).
  • He Hua-Wei*, Li Jie*, Zhao Tong-Jin, Ma Yong, Shi Feng, Zhou Hai-Meng. Exploration of the polar microenvironment around the reactive cysteine in rabbit muscle creatine kinase. Int. J. Biol. Macromol. 2007 41(4):361-8 (*, co-first author).
  • Shi Feng*, Zhao Tong-Jin*, He Hua-Wei, Li Jie, Zeng Xian-Gang, Zhou Hai-Meng, Wu Ping. Sodium barbital is a slow reversible inactivator of rabbit-muscle creatine kinase. Biochem. Cell Biol. 2006 84(2):142-7 (*, co-first author).
  • Zhang Jun, He Hua-Wei, Wang Qi, Yan Yong-Bin. Sequential events in ribonuclease A thermal unfolding characterized by two-dimensional infrared correlation spectroscopy. Protein Pept. Lett. 2006 13(1):33-40.
  • Yan Yong-Bin, Zhang Jun, He Hua-Wei, Zhou Hai-Meng. Oligomerization and aggregation of bovine pancreatic ribonuclease A: characteristic events observed by FTIR spectroscopy. Biophys. J. 2006 90(7):2525-33.
  • He Hua-Wei, Zhang Jun, Zhou Hai-Meng, Yan Yong-Bin. Conformational change in the C-terminal domain is responsible for the initiation of creatine kinase thermal aggregation. Biophys. J. 2005 89(4):2650-8.
  • Meng Fan-Guo*, Hong Yuan-Kai*, He Hua-Wei, Lyubarev A. E., Kurganov B. I., Yan Yong-Bin, Zhou Hai-Meng. Osmophobic effect of glycerol on irreversible thermal denaturation of rabbit creatine kinase. Biophys. J. 2004 87(4):2247-54 (*, co-first author).
  • Yan Yong-Bin, Wang Qi, He Hua-Wei, Zhou Hai-Meng. Protein thermal aggregation involves distinct regions: sequential events in the heat-induced unfolding and aggregation of hemoglobin. Biophys. J. 2004 86(3):1682-90.
  • Yan Yong-Bin*, Wang Qi*, He Hua-Wei, Hu Xin-Yao, Zhang Ri-Qing, Zhou Hai-Meng. Two-dimensional infrared correlation spectroscopy study of sequential events in the heat-induced unfolding and aggregation process of myoglobin. Biophys. J. 2003 85(3):1959-67 (*, co-first author).

联系地址: 400716,西南大学 家蚕基因组生物学国家重点实验室



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